Congenital Diaphragmatic Hernia Pediatric Research and Clinical Trials

Congenital diaphragmatic research and innovation

Boston Children's Hospital and its Advanced Fetal Care Center are committed to cutting-edge clinical research and innovative medicine and surgery. We want to make a difference in your prenatal care, the care of your baby-to-be and the care of generations to come. The goal is to continue to find ways to detect and treat fetal disorders through medical and surgical innovation. 

Find out more about the AFCC's milestones in care

Taking fetal stem cells into clinical trials

The lab of Boston Children's surgeon Dario Fauza, MD, has come closer than any in the country to using fetal stem cells, taken from amniotic fluid during pregnancy, to fix congenital defects in babies. These stem cells can form many of the tissues needed by surgeons, including muscle, skin, cartilage and even bone. Fauza's strategy is to gather these cells during amniocentesis and have engineered tissues ready to implant when the baby is born

Looking for the genetic roots of congenital diaphragmatic

The Congenital Diaphragmatic Hernia (CDH) Program at Boston Children’s is currently engaged in a study with the goal of identifying the genes responsible for CDH and abnormal lung development.

We hope that by learning more about the causes of CDH we will be able to improve the care and outcome for the next generation of babies born with CDH. Long term, the results from this study may lead to simpler, more effective treatments for children with CDH. For more information about participation in the study, visit our research page.