Cleft Hand | Symptoms & Causes

What causes cleft hand?

There’s a clear genetic basis for typical cleft hands. Inheritance of cleft hand is autosomal dominant. This means if a parent has the condition, the child has a 50 percent chance of having it as well.

Cleft hand can occur in isolation or as part of a genetic syndrome, such as cleft lip and palate or ectrodactyly (split hand-split foot malformation).

What are the symptoms of cleft hand?

In a cleft hand, there are always clefts in the central (middle fingers) part of the hand, and they’re usually V-shaped. However, clefts can also occur on the thumb (radial) side of the hand, or, less commonly, on the little (ulnar) finger side. They can also occur in various combinations.

In the majority of children who have a cleft hand, it may be an isolated occurrence, affecting only the hand. But your doctor will check for other associated deformities or syndromes, including:

  • cleft lip and palate
  • foot abnormalities
  • protrusion of brain membrane
  • conditions affecting the heart and digestive systems
  • (rarely) deafness