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What's the treatment for Alagille syndrome?
There are two primary goals of treatment:
Your child may be prescribed ursodeoxycholic acid to increase the flow of bile from the liver and lower cholesterol levels in the blood.
Antihistamines and other medications may be given to help relieve the itchiness associated with the decreased bile flow.
Nutritional supplements may be needed to help your child digest types of dietary fat that can be difficult for the body to absorb due to reduced bile flow.
Children may have difficulty getting enough vitamins, specifically vitamins A, D, E and K, due to problems with digesting dietary fat.
Surgery is generally not recommended to treat liver disease in Alagille syndrome, although a surgical biopsy may be necessary to accurately diagnose the condition during your child's infancy.
Currently, there is no surgical procedure that can correct the bile duct system. However, in the minority of children with advanced liver disease due to Alagille syndrome, liver transplantation may be a consideration.
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