Acute Kidney Injury Pediatric Research and Clinical Trials

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Contact the Division of Nephrology

Boston Children’s is home to the world’s most extensive research enterprise at a pediatric hospital. In our End Stage Renal Disease Program—which includes the dialysis unit and our Kidney Transplant Program—our treatment is influenced by our research.

We also have a great number of partnerships with top research, biotech and health care organizations and we work together to improve kids’ health.

One of these is the Transplant Research Center (TRC), which provides a rich environment for collaboration of scientists and physicians in the areas of transplantation and immunology.

If your child has end-stage renal disease, dialysis can filter his blood, but not take over the other roles of the kidney, such as regulating the amounts of some important vitamins and minerals released into the bloodstream and controlling blood pressure. For that, your child needs to take medication and follow a special diet. Our researchers are currently involved in several clinical trials to assess the safety and efficacy of medications aimed at fulfilling this pharmaceutical component of treating end-stage renal disease.

We’re committed to developing better anti-rejection medication with the goal of more successful transplants and fewer side effects. Read more about how Boston Children's doctor/researchers are at the forefront of the effort to produce better anti-rejection medication.

Catching AKI early

Michael Ferguson, MD, is collaborating with researchers at the Brigham and Women’s Hospital to discover biological markers—molecular signs that a condition is present—of acute kidney injury. This work aims to help us identify children with AKI more quickly, so that further damage to the kidney may be avoided. This research also aims to help us predict how the AKI will resolve in various situations.

We currently participate in more NIH-sponsored pediatric kidney transplant research studies than any other program in the nation.

Boston Children’s is so much more than a hospital—it’s a community of researchers, clinicians, administrators, support staff, innovators, teachers, patients and families, all working together to make the impossible possible. ”
- Sandra L. Fenwick, President and CEO

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