Childen's Hospital Boston
International Visitorsdotted lineRequest Appointmentdotted lineDirections
 advanced search
About Us Find a Specialist Locations Careers Press Room Giving To
Clinical Services For Patients & Families For Health Professionals Research
My Child Has
or find by letter:  A-F  G-L  M-R  S-Z

Cardiovascular Program

 Cardiovascular Program
 New Research & Treatments
  Investigators
 Email this page
 Printer Friendly
 X
Flower Preventive Cardiology
Back to New Research & Treatments
The medical staff at the Preventive Cardiology Clinic are committed to helping reduce high rates of heart disease in the United States, by heading it off at its earliest stages.

At a time when obesity and diabetes are on the rise among American children, the Preventive Cardiology team treats those who have these and other problems that may contribute to the development of heart disease in early adulthood.

As part of its mission to advance scientific understanding of atherosclerosis (the gradual hardening and narrowing of arteries that sets the stage for a heart attack or stroke) the Preventive Cardiology Clinic serves as the base of operations for a wide range of research programs. Research is aimed at furthering the understanding of the mechanisms behind atherosclerosis, as well as studying more effective and safe treatments for cholesterol and high blood pressure problems in childhood.

Preventive Cardiology Clinic researchers are involved with studies on the following topics:

  • Metabolic Syndrome - Metabolic syndrome is a condition defined as having three or more leading risk factors for heart disease. These risk factors include obesity, pre-diabetes (impaired fasting glucose or insulin resistance), high blood pressure, low HDL cholesterol and elevated triglycerides. Metabolic syndrome in adults is relatively well understood, but how prevalent this syndrome is in the pediatric population is less studied. Researchers at Children's Hospital Boston performed a study that looked at the risk factors measured in 1,960 adolescents and found that two-thirds of the group had at least one risk factor for heart disease, and nearly 10 percent had metabolic syndrome. The results, published in Circulation: Journal of the American Heart Association, further underscores the need to start heart disease prevention efforts early in life.

  • Inflammation: - In recent years, inflammation has become a medical phenomenon, as researchers uncover its role in disease development and doctors offer medical tests that measure inflammation and treatments aimed at controlling it. Numerous studies in adults suggest that inflammation, the body's way of responding to illness, plays a key role in atherosclerosis. Studies also show that the presence of high levels of the inflammation marker C-reactive protein (CRP) can predict heart attack or stroke in adults. Researchers at Children's Hospital Boston are enrolling children in a large study that will help enhance understanding of the inflammation process.

  • Nutritional treatement of overweight adolescents with cardiovascular risk factors - Preventive Cardiology Clinic clinicians are currently enrolling overweight teens with high triglycerides, low HDL (good cholesterol), high blood pressure, and/or insulin resistance, in a study that will compare the effects of two diets on modifying these particular risk factors. The study provides participants with all of their food for the 8 week study at an amount designed to induce weight-loss. Study personnel will then monitor participants closely for changes in weight and risk factors.

  • Hypertriglyceridemia in Children - To better understand elevated triglycerides levels in childhood, clinicians in the Preventive Cardiology Clinic are reviewing the characteristics of children with this disorder, as well as examining mediations and family history, weight, blood pressure, recommended dietary changes, and accompanying medical conditions, and the change in triglycerides over time. Clinicians hope this will help take better care of children with high triglycerides. An interventional trial of omega-3 fatty acids is planned in the near future.
 X
Contact Us Site Map Privacy Accessibility Give Now en Español