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Children with Moyamoya disease usually come into the hospital or emergency room with symptoms of stroke - weakness on one side of the body, slurred speech or impaired vision. These symptoms may occur and then gradually subside or they may appear suddenly and remain permanent.
Sometimes the disease will cause headaches or seizures (a sudden change in consciousness or behavior, due to changes in brain electrical activity. Seizures may result in loss of consciousness, involuntary movements such as twitching or shaking, abnormal sensations or visual disturbances. Possible causes include epilepsy, trauma, meningitis, tumor, stroke and hydrocephalus).
Brain hemorrhages are a rare occurrence for children with moyamoya disease, although they occur more frequently in young adults with the disease. Most patients have one form of the condition, and it is extremely rare to see the childhood form of the disease evolve later in life to the hemorrhagic form. Symptoms of hemorrhage include:
nausea
vomiting
intense headache
lethargy
vision changes
weakness
numbness on one side or in one part of the body.
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