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Clinical Training: Clinical Statistics

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Hematology

	New patients/year	Total active patients
Red cell disorders
Sickle cell disease	20	220
Hereditary spherocytosis	10	100
Thalassemia major/intermedia	10	60
Other hereditary disorders	22	45
Anemia workups/consultations	350	150
White cell disorders
Leukopenia, neutropenia, leukocytosis	120	60
Hereditary WBC function disorders	3	15
Coagulopathies
von Willebrand disease	50	>200
Hemophilia	8	130
Other coagulation defects	5	30
Thrombotic disorders, hypercoagulation	100	150
Coagulation consults	400	---
Platelet disorders
ITP	55	150
Other	10	50
Bone marrow failure syndromes	10	50

Ambulatory -2500 hematology patient visits per year, approximately 600 chronic transfusion visits/year (thalasemia ajoe, sickle cell disease, bone marrow failure, rare anemias). Inpatient 5+/-3 patients on the hematology inpatient service daily, 5+/-4 consults daily on hematology service, plus 1-4 consults daily on anticoagulation service.

Oncology

	New patients/year	Total active patients
Histiocytosis	1	20
Leukemia
ALL	61	93
AML	10	26
Lymphoma
Hodgkin's disease	17	23
Non-Hodgkin's lymphoma	22	26
Sarcomas	53	51
Wilm's tumor	9	12
Neuroblastoma	24	50
Brain tumors	80	90
Other tumors	57	81

Ambulatory (Jimmy Fund Clinic)- 11,500 oncology and stem cell transplantation patient visits/year.

Inpatient (6 North)- average of 16 oncology patients per day on 21-bed hematology/oncology ward plus 8-10 off-service oncology patients and oncology consults.

In addition to the patients diagnosed and treated at Children's Hospital Boston and Dana-Farber Cancer Institute, we see many patients referred from other centers with difficult oncologic problems.

Stem Cell Transplantation

	Transplants/year
Type of transplant	2006	2007
Autologous	23	12
Allogeneic	47	53
Donor source
Bone marrow	38	46
Cord blood	8	5
Peripheral blood stem cells	24	14
Conditions treated
Leukemia	34	36
Lymphoma	7	5
Hematologic disorders	10	9
Neuroblastoma, solid turmors, brain tumors	13	12
Metabolic diseases, Immunodeficiency	6	3

Inpatient (6 West)- average of 10-12 transplant patients per day on a newly renovated 13-bed stem cell transplant unit. New patient evaluations and follow-ups take place at Dana-Farber's Jimmy Fund Clinic. The stem cell transplantation group consists of 13 attending physicians, 1 physician's assistant, two nurse practioners, and a two transplant coordinators.

Cooperative Group, Centers and Funded Research Networks

Cooperative Cancer Group	Children's Oncology Group (COG) New Approaches in Neuroblastoma Therapy Phase I Program for Children's Oncology Group
Nationally Funded Centers
	Sickle cell disease	Boston Sickle Center
		New England Pediatric Sickle Cell Consortium
	Hemophilia	Boston Hemophilia Center
	Cancer	Dana-Farber/Harvard Cancer Center
	Genetics	Boston Center for Genetic Blood Diseases
Funded Research Networks
	Pediatric Research	Glaser Clinical Research Network
	Thalassemia	Thalassemia Clinical Research Network


					Children's Hospital Boston is the primary pediatric teaching hospital of Harvard Medical School

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