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For some patients we may also recommend a bone marrow biopsy and aspiration. This surgical procedure collects a sample of the bone marrow, the substance that produces white blood cells, red blood cells and platelets.
After the tissue sample is collected, our pediatric hematopathologists will examine it under the microscope to determine if it is Hodgkin's lymphoma and the exact type. In addition to examining the tissue under the microscope, additional tests (often called stains or "immpox") are done to be certain about the diagnosis. Sometimes, molecular tests may also be required. Pathologists will usually assign a specific type of Hodgkin's: nodular sclerosing, mixed cellularity, lymphocyte depleted, or lymphocyte predominant. The first three types are sometimes called "classical" Hodgkin's.
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