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In some cases, the cause of bone marrow failure cannot be determined.
Acquired aplastic anemia in children can occur for no known cause (idiopathic), or as the result of another illness or condition. A history of some infectious diseases such as hepatitis, Epstein-Barr virus (EBV), cytomegalovirus (CMV), or human immunodeficiency virus (HIV); autoimmune illnesses such as lupus; exposure to toxins such as heavy metals and high doses of radiation; and certain medications can lead to acquired aplastic anemia.
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