The two research fellowship years aim at broadening the fellow's understanding of Nephrology disease. One of the unique aspects of our training program is the ability to participate in ongoing research efforts in the Nephrology Research Laboratories. The Director of Nephrology Research, Dr. Mohamed Sayegh, and Dr. David Briscoe advise fellows in the selection of a basic science research project approximately six months prior to initiating the laboratory research fellowship years. Our laboratory research faculty share a common interest and expertise in:
- cellular and molecular biology
- immunology and Nephrology development
- transplantation biology
- cell biology
- transport mechanisms present in epithelia of the kidney, lung, and cell of the central nervous system
Our transplant immunology research program focuses on mechanisms of alloimmunity, functional interactions between lymphocytes and endothelial cells as well as immunologic tolerance. In addition, our Nephrology development program has a focused interest in molecular regulation of organogenesis.
A specific interest of the clinical research faculty is the pathophysiology of chronic Nephrology disease in children. Ongoing studies address growth abnormalities and defining risk factors influencing outcome of children undergoing chronic dialysis and Nephrology transplantation therapies.
The fellowship schedule is designed to promote optimal exposure to all aspects of Pediatric Nephrology during the training years. First year fellows are expected to prepare and present clinical conferences each month. In addition, fellows actively participate in medical student teaching and house officer conferences. In subsequent years, the fellow participates in the research conferences and makes periodic presentations of his/her research efforts at individual laboratory and divisional research laboratory seminars and journal clubs. Fellows also actively participate in medical student teaching and house officer conferences. Lastly, all research fellows are encouraged to attend Harvard wide seminars specific to their research interest including the Harvard Medical School Seminars in Immunology and Vascular Biology.
Since few pediatric nephrologists can operate separately from an academic institution or large affiliated medical center, all aspects of our training program are designed to develop skills as both a clinical scientist and teacher. Our training program provides the opportunity to develop interests in all aspects of the clinical science of Pediatric Nephrology.
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