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Nephrology

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Flower Training
The fellowship program provides broad training in all the major areas of nephrology with opportunities to develop clinical and research skills. There are three years of training - one clinical year and two years of laboratory research. The training program meets the requirements for certification by the Sub-board of Nephrology of the American Board of Pediatrics and is supported by an NIH Training Grant.
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Fellows 2008
Complete Description of the Training Program (PDF File)
Fellowship Application Form
Overview of Fellowship Training Program
The Division of Nephrology at Children's is currently the largest pediatric nephrology division in the United States. The Division aims to develop academic pediatric nephrologists who will be able to establish independent investigative careers in areas relevant to the understanding of childhood nephrology diseases. The fellowship program provides broad training in all the major areas of nephrology with opportunities to develop clinical and research skills.
Clinical Training

The clinical training year provides the fellow with extensive exposure to a wide variety of clinical problems in pediatric nephrology. This is accomplished by full participation of fellows in all the patient care activities within the division, including:

  • direct care of nephrology inpatients
  • serving as consultant to both inpatient and outpatient divisional programs
  • care of the transplant and pediatric dialysis outpatients
  • care of the general Nephrology clinic outpatients
Fellows become proficient in all technical aspects of nephrology such as performing nephrology biopsies, hemodialysis and peritoneal dialysis. In addition, the fellows acquire experience through the Department of Pathology in the interpretation of light, immunofluorescence and electron microscopy, and through the Department of Radiology in the interpretation of uroradiologic studies.

The Division has two clinical services: the End-Stage Nephrology Disease Service (dialysis and transplantation); and the General Nephrology Consult Service. Each fellow spends approximately equivalent time on the End Stage Disease and the Consult Service. The fellow is responsible for:

  • supervising the care of all inpatients who are followed by the Division of Nephrology
  • providing consultative services for Children's and the neonatal intensive care unit at the Brigham and Women's Hospital, Beth Israel Deaconess and other affiliated community hospitals
  • performing acute dialysis and hemofiltration as well as all percutaneous renal biopsies
Research
The two research fellowship years aim at broadening the fellow's understanding of Nephrology disease. One of the unique aspects of our training program is the ability to participate in ongoing research efforts in the Nephrology Research Laboratories. Fellows are advised in the selection of a research project approximately six months prior to initiating the laboratory research fellowship years. Our laboratory research faculty share a common interest and expertise in:
  • cellular and molecular biology
  • immunology and Nephrology development
  • transplantation biology
  • cell biology
  • transport mechanisms present in epithelia of the kidney, lung, and cell of the central nervous system
Our transplant immunology research program focuses on mechanisms of alloimmunity, functional interactions between lymphocytes and endothelial cells as well as immunologic tolerance. In addition, our Nephrology development program has a focused interest in molecular regulation of organogenesis.

A specific interest of the clinical research faculty is the pathophysiology of chronic Nephrology disease in children. Ongoing studies address biomarkers of renal disease and novel transplantation immunosuppressive therapies.

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