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Bone Health Program

 Bone Health Program
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 Adolescent Medicine
 Endocrinology
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The Bone Health Program has been actively involved in exploring the causes and symptoms of pediatric low bone density and researching new and improved treatments. Recent research interests have included:
  • Use of Adrenal and Gonadal Hormone Replacement to Prevent Osteoporosis in Anorexia Nervosa:
    A randomized, double-blind placebo-controlled trial examining the effect of oral DHEA and estrogen/progestin replacement on bone turnover, density and strength in patients with anorexia nervosa.
  • Effect of Hormonal Add-Back Therapy in Adolescents Treated with (GnRH) Agonist Therapy for Endometriosis:
    A randomized, double-blinded trial to measure the bones of healthy adolescents with patients with diseases, like anorexia nervosa and endometriosis can be compared.
  • Optimization of Vitamin D Stores and Its Impact on the Bone Health and Disease Outcomes of Children and Adolescents with IBD:
    Vitamin D is important for growing and maintaining healthy bones throughout life, and this is particularly important since children with IBD frequently have low bone density.
  • Bioavailability of Vitamin D in Adolescents and Young Women with Anorexia Nervosa:
    This protocol is to compare how vitamin D is absorbed and used by the body in young women with anorexia nervosa and in healthy adolescents.

  • Use of Farnesyltransferase inhibitor (FTI) Lonafarnib for Hutchinson-Gilford Progeria Syndrome (HGPS) and progeroid laminopathies:
    This protocol measures an experimental drug's effect using many tests in hopes that this drug will have therapeutic effect on progeria.

Research by Catherine Gordon, MD, MSc, Director of the Bone Health Program

Research by Ingrid Holm, MD, MPH, Associate Director of the Bone Health Program

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