Meet our Team

Isaac Kohane, MD, PhD

Chair, Boston Children’s Hospital Informatics Program
Co-Director, Center for Biomedical Informatics, Lawrence J. Henderson Professor of Pediatrics and Health Sciences and Technology, Harvard Medical School
Director, HMS Countway Library of Medicine

“We are very enthusiastic about this unique competition. The CLARITY Challenge is designed to help us—as a medical community—overcome the key stumbling blocks to realizing the potential for genomic information to revolutionize the way we treat disease and care for patients. While the Challenge involves finding clinically meaningful genomic information for three families, what we learn as a result about best practices and processes ultimately stands to impact all patients.”

David Margulies, MD

Director, The Gene Partnership at Boston Children’s Hospital
Divisions of Genetics and Developmental Medicine, Boston Children’s Hospital
Boston Children’s Informatics Program
Center for Biomedical Informatics, Harvard Medical School

“The CLARITY Challenge is closely tied to the goals of the Gene Partnership, our multi-disciplinary effort aimed at rapidly accelerating the use of genomic information in research and everyday patient care throughout our institution. I’m grateful to those who are sponsoring this effort. By marshaling the creativity of teams from around the world, this event will likely advance the art of genomic interpretation. We are dedicated to pursuing long-term goals while delivering practical, near-term benefits.”

Alan Beggs, PhD

Director, Manton Center for Orphan Disease Research
Sir Edwin and Lady Manton Professor of Pediatrics, Harvard Medical School

“Unraveling the mysteries behind rare diseases is intimately tied to our understanding of the genetic factors responsible for these conditions. We believe using genomic information to advance care for patients with rare diseases on a large scale is an attainable goal, which The CLARITY Challenge will bring us closer to achieving. Expanding our understanding of rare diseases will result in broad benefits for human health. The challenge is enormous, but the possibilities are limitless.”

Elizabeth DeChene, MS CGC Genetic Counselor
Manton Center for Orphan Disease Research
Children’s Hospital Boston

Meghan Connolly, MS CGC, Genetic Counselor
Manton Center for Orphan Disease Research
Children’s Hospital Boston

Katherine Flannery
Program Manager
Center for Biomedical Informatics
Harvard Medical School

Dianne McCarthy, JD
Chief Counsel for Research Affairs
Children’s Hospital Boston