Steven J. Fishman, MD
|Hospital Title||Senior Associate in Surgery|
|Academic Title||Associate Professor|
300 Longwood Avenue
Boston MA 02115
The goals of Dr. Fishman's research include:
- To effect permanent luminal obliteration of vascular malformations using tissue engineering and angiogenesis inhibition to enhance existing intravascular therapies.
- To clarify the subtypes of pediatric liver hemangiomas, predict their natural history, and optimize their management.
- To develop mechanisms to enlarge short segments of esophagus and intestine.
The translational implications of Dr. Fishman's work:
- Vascular malformations can often be controlled or nearly obliterated with intravascular sclerotherapy or embolization of the luminal spaces. However, recanalization and clinical recurrence are commonplace. We hope to make luminal obliteration permanent, eliminating the need for repeated procedures and deforming surgical procedures.
- Liver hemangiomas, previously believed to be homogeneous, occur in several types and patterns. Clarifying their phenotypes and behaviors will facilitate improved survival and avoid needless morbidity.
- Infants born with esophageal atresia have a disrupted, often very short esophagus. When the two ends cannot be brought together, the esophagus is often surgically replaced with other, less adequate organs. Facilitating growth of the shortened esophagus may allow the native esophageal tissues to be connected, eliminating the need for replacement with colon or stomach.
About Steven Fishman
Dr. Fishman completed his residency in general surgery at the Hospital of the University of Pennsylvania. He was a Pediatric Surgical Fellow at Children's Hospital Boston.
- Downard CD, Kim HB, Laningham F, Fishman SJ. Esophageal atresia, duodenal atresia, and unilateral lung agenesis: a case report. J Pediatr Surg 2004, in press.
- Huang SA, Tu HM, Harney JW, Venihaki M, Butte AJ, Kozakewich HPW, Fishman SJ, Larsen PR. Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. N Engl J Med 2000; 343(3): 185-189.
- Fishman SJ, Mulliken JB, Leichtner AM, Burrows PE. Gastrointestinal manifestations of vascular anomalies in childhood: varied etiologies require multiple therapeutic modalities. J Pediatr Surg 1998; 33(7): 1163-1167.
- Fishman SJ, Smithers CJ, Folkman J, Lund DP, Burrows PE, Mulliken JB, Fox VL. Blue rubber bleb nevus syndrome: surgical eradication of gastrointestinal bleeding. Ann Surg 2005; 241(3): 523-528.
- Christison-Lagay ER, Burrows PE, Alomari A, Dubois J, Kozakewich HP, Lane TS, Paltiel HJ, Klement G, Mulliken JB, Fishman SJ. Hepatic hemangiomas: Sub-type classification and development of a clinical practice algorith and registry. J Pediatr Surg 2007; 42(1): 62-68.
- All of Dr. Fishman's publications on PubMed