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  Children's Hospital Research  Children's Hospital Labs
Thomas J. Sandora, MD, MPH  Children's logo  Harvard logo
 Thomas Sandora MD
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   Department  Infectious Diseases
   Hospital Title  Associate Physician in Medicine
   Academic Title  Assistant Professor of Pediatrics
   Phone  617-919-2900
   Fax  617-730-0254
   Email  Thomas Sandora
   Location  300 Longwood Avenue
Boston
MA 02115
Research Overview

Dr. Sandora conducts epidemiologic and clinical research, having obtained a Masters in Public Health degree from Harvard in 2004. His particular areas of interest include hospital epidemiology, infection control, and hand hygiene. He also conducts research in medical education.

Gastrointestinal (GI) and respiratory tract infections are common among children attending out-of-home childcare, and these infections are often transmitted to family members in the home. Dr. Sandora was the principal investigator for the Healthy Hands Healthy Families study, which was the first randomized controlled trial to demonstrate that alcohol-based hand sanitizers (as part of a multifactorial hand hygiene intervention) can reduce illness transmission in the homes of families who have children enrolled in childcare programs. He also conducted a clinical trial demonstrating that a school-based disinfection and hand hygiene intervention can reduce absenteeism from gastrointestinal illness among elementary school students.

Dr. Sandora also conducts research about preventing infections in the hospital. He has been involved in implementing and studying a systematic way to reduce central line-associated bloodstream infections (CLA-BSI) in a pediatric cardiac intensive care unit, as well as investigating risk factors for these infections. He is currently working on the development of a prediction rule for CLA-BSI in pediatric intensive care unit patients to help identify high-risk children who might benefit from further interventions to prevent infections.

Dr. Sandora?s research interests also include community-acquired pneumonia (CAP), a common pediatric infection for which management is highly variable. National measures to assess the quality of care for pediatric patients with pneumonia are lacking. He completed a study to assess the applicability of quality indicators that are recommended for adults with CAP, such as choice of antibiotic and time to antibiotic administration, and found that these indicators are often not achieved in children and are not always applicable because of differences between adult and pediatric patients.

Finally, in his role as the assistant program director for the Boston Combined Residency in Pediatrics, Dr. Sandora mentors residents and conducts medical education research. Past projects include a national survey of pediatric program directors regarding procedural training, and the creation and assessment of a procedural skills curriculum for pediatric residents and for medical students. He will next study the impact of a clinical journal club on the acquisition of critical appraisal skills by residents.

About Thomas Sandora
Dr. Sandora received his MD degree from Harvard Medical School and his MPH degree from the Harvard School of Public Health. He completed his pediatrics residency, chief residency, and infectious diseases fellowship at Children's Hospital Boston.

Key Publications
  • Sandora TJ, Shih MC, Goldmann DA. Reducing absenteeism from gastrointestinal and respiratory illness in elementary school students: a randomized, controlled trial of an infection-control intervention. Pediatrics 2008; 121:e1555-62.
  • Costello JM, Morrow D, Graham DA, Potter-Bynoe G, Sandora TJ, Laussen PC. Systematic intervention to reduce catheter-associated bloodstream infections in a pediatric cardiac intensive care unit. Pediatrics 2008; 121:915-23.
  • Costello JM, Graham DA, Morrow D, Potter-Bynoe G, Sandora TJ, Laussen PC. Risk factors for central line-associated bloodstream infection in a pediatric cardiac intensive care unit. Pediatr Crit Care Med. In press
  • Sandora TJ, Desai R, Miko BA, Harper MB. Assessing quality indicators for pediatric community-acquired pneumonia. Am J Med Qual. In press.
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