Leo Wang, MD, PhD
| Department | Pediatric Hematology/Oncology/Hematopoietic Stem Cell Transplant |
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| Hospital Title | Staff Physician and Clinical Instructor | |
| Academic Title | Instructor in Pediatrics | |
| Phone | 617-632-4203 | |
| Fax | 617-632-4410 | |
| Leo Wang | ||
| Location | 1 Joslin Place, Boston MA 02215 |
Research Overview
Dr. Wang conducts basic science research in the laboratory of internationally-renowned stem cell expert Amy Wagers at the Harvard Stem Cell Institute. Dr. Wang investigates questions of hematopoietic stem cell function in health and disease, with a particular focus on the effects of the bone marrow microenvironment on hematopoiesis. Dr. Wang was recently named a Damon Runyon-Sohn Pediatric Cancer Fellow in support of this work. Dr. Wang’s clinical interest is in pediatric hematopoietic stem cell transplantation, where he is an Attending Physician.
About Leo Wang
Dr. Wang graduated from Yale University, and received his MD and Ph.D. degrees from the University of Chicago. His graduate thesis research focused on the role of the pre-B cell receptor in B cell development. He trained in pediatrics at the Children’s Hospital of Philadelphia, where he performed research in gene therapy for hemophilia. Dr. Wang completed his fellowship training in the Division of Hematology/Oncology at Children’s Hospital Boston and the Dana-Farber Cancer Institute.
Key Publications
- Nabors L.K., Wang L.D., Wagers A.J., and Kansas G.S. “Overlapping roles for endothelial selectins in hematopoietic stem/progenitor cell homing to bone marrow.” (Submitted)
- Wang L.D. and A.J. Wagers “On the origin and differentiation of hematopoietic stem cells and their niches.” (2011) Nat. Rev. Mol. Cell Biol. 12 (10): 643-655.
- Wang L.D., Lopes J., Cooper A.B., Dang-Lawson M., Matsuuchi L., and Clark M.R. “Selection of B lymphocytes in the periphery is determined by the functional capacity of the B cell antigen receptor.” (2004) Proc. Natl. Acad. Sci. USA. 101(4): 1027-32.
- Atwood W.J., Wang L., Durham L.C., Amemiya K., Traub R.G., and Major E.O. “Evaluation of the role of cytokine activation in the multiplication of JC virus (JCV) in human fetal glial cells.” (1995) J. Neurovirol. 1(1): 40-49.
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Gelbard H.A., Nottet H.S., Swindells S., Jett M., Dzenko K.A., Genis P., White R., Wang L., Choi Y.B., Zhang D., Lipton S.A., Tourtellotte W.W., Epstein L.G., and Gendelman H.E. “Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin.” (1994) J. Virol. 68(7): 4628-35.
