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Phase I/II Trial of Topical Clotrimazole in Pediatric and Adult Patients with Pouchitis (CAPTURE)

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Pouchitis is an inflammatory process that occurs in the majority of patients with ulcerative colitis that have had their colons removed and have ileal pouches. Pouchitis can cause a variety of symptoms including abdominal pain and diarrhea and can be very resistant to currently available therapies in some patients. This FDA-sponsored trial will assess the effectiveness of clotrimazole enemas in children and adults with pouchitis.

Contact: Paul A. Rufo, M.D., M.M.Sc. or Tracee Cook, PNP (617-355-4204)
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