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Common Strabismus

Concomitant (or common) strabismus occurs when the angle of deviation of the eyes remains constant independent of the direction of gaze and includes those conditions listed in the table below.

Name of Disorder
Esotropia:
infantile
intermittent
accommodative
non accommodative
Exotropia
Hypertropia
Dissociated vertical deviation
Microstrabismus
Monofixation syndrome
Very little is known about the pathogenesis of common strabismus and, although there is significant evidence for a genetic basis, no disease or susceptibility genes have been identified.

We are commencing research in collaboration with Department of Ophthalmology and the General Clinical Research Center at Children's Hospital Boston to identify disease and susceptibility genes for these forms of strabismus and hope this work will lead to identification of individuals at risk, improve our ability to detect and prevent amblyopia (reduced vision in a healthy eye) and loss of binocular vision, and provide insight into the pathogenesis of these common disorders.

Please contact Caroline Andrews to obtain further information on this research study.

  
News
We have obtained funding from the National Eye Institute to develop the infrastructure necessary for the large-scale identification of common strabismus disease and susceptibility genes.

Population, twin and family studies support common strabismus as a complex genetic trait and we are now ready to start recruiting families in which there are 3 or more affected members meeting the criterion displayed on the left hand page. Please click below to access our information brochure. In addition, please contact: Caroline Andrews for further information.

Participation in the study is straightforward, and includes informed consent, a medical history form for the participant to fill out, documentation of the patient's examination, and a blood or saliva sample from the participant. These studies are approved by the Institutional Review Board of Children's Hospital Boston and funded by the National Eye Institute.

Information brochure
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