Research Faculty

Lawrence Rhein, MD

 

Department Newborn Medicine
Hospital Title Director, Center for Healthy Infant Lung Development
Academic Title Assistant Professor of Pediatrics
Phone 617-355-3185
Fax 617-355-0084
Email Lawerence Rhein
Location 333 Longwood Ave, 5th floor

Research Overview

We have utilized continuous pulse oximetry in multiple different applications. We have projects that include:

  1. Determination of optimal methods to safely wean premature infants from supplemental oxygen
  2. Determination of optimal target saturations to minimize neurodevelopmental morbidities
  3. Identification of oxygen saturation patterns to predict outcomes including silent aspiration, or ROP.
  4. Identification of oxygen saturation patterns to predict respiratory fragility during upright positioning.
     

About Lawrence Rhein

I went to Harvard College and then completed medical school at the University of Pennsylvania. I completed residency in the Boston Combined Residency in Pediatrics (Children’s Hospital Boston and Boston Medical Center) and then Chief Residency at Children’s Hospital Boston. I then completed a dual fellowship in Pediatric Pulmonology and Newborn Medicine at Children’s Hospital Boston.

I spent several years performing laboratory research, focusing on murine models of host defense against lung pathogens. I then transitioned into clinical/translational research.

I am originally from the Boston area, and have a beautiful family, including 3 small children. I am one of triplets, and also have a younger sister.

Key Publications

RHEIN L, Konnikova L, McGeachey A, Pruchniewski M, and Smith VC. The Role of Pulmonary
Follow-up in Reducing Health Care Utilization in Infants with Bronchopulmonary Dysplasia.
Clinical Pediatrics 2011 (accepted for publication).

RHEIN L, Simoneau, T., Davis, J., Correia, C., Ferrari, D., Monuteaux, M. and Gregory, M.
(2011), Reference values of nocturnal oxygenation for use in outpatient oxygen weaning
protocols in premature infants. Pediatric Pulmonology. doi: 10.1002/ppul.21562

DeGrazia M, Guo Y, Wilkinson A, and RHEIN LM. Weight and Age as Predictors for Passing the
Infant Car Seat Challenge. Pediatrics. Mar 2010; 125: 526-531.