DNA photo
Children's Hospital Research Children's Hospital Labs
Todd Golub, MD Children's logo Harvard logo
Todd Golub, MD
X X
   Department  Hematology/Oncology
   Hospital Title  Associate in Medicine
   Academic Title  Associate Professor of Pediatrics
   Phone  617-632-4903
   Fax  617-632-4850
   Email  Todd Golub
   Location  44 Binney Street
Boston
MA 02115
Research Overview
Todd Golub's laboratory focuses on the genetic basis of cancer, with particular emphasis on the utilization of new genomics and computer science approaches to cancer diagnosis and treatment planning. The laboratory has pioneered the use of DNA microarrays, or 'DNA chips,' for cancer diagnosis and is currently extending these techniques to gain insight into the molecular basis of human cancer. Part of this research effort involves the integration of computer science experts into the research group to extract clinically meaningful patterns from complex genetic information within tumors.
About Todd Golub

Todd Golub received his MD from the University of Chicago Pritzker School of Medicine. He competed an internship, residency, and fellowship at Children's Hospital Boston/Dana-Farber Cancer Institute.

He is the recipient of numerous honors and awards, including the Cornelius Rhoads Memorial Prize, American Association for Cancer Research, 2002 and the Judson Daland Prize for Outstanding Achievement in Clinical Investigation, American Philosophical Society, 2001. He was named Inventor of the Year (Health Category) for 2000 by Discover Magazine.
Key Publications
  • Antipova A, Tamayo P, Golub TR. A strategy for oligonucleotide microarray probe reduction. Genome Biol 2002; 3:research0073.

  • Armstrong SA, Staunton JE, Silverman LB, Pieters R, den Boer ML, Minden MD, Sallan SE, Lander ES, Golub TR, Korsmeyer SJ. MLL translocations specify a distinct gene expression profile, distinguishing a unique leukemia. Nature Genetics 2002; 8:68-74.

  • Lessnick SL, Dacwag CS, Golub TR. EWS/FLI induces p53-dependent growth arrest in primary human fibroblasts. Cancer Cell 2002; 1:393-401.
X X
Copyright 2004 Children's Hospital Boston