Todd Golub, MD
| Department | Hematology/Oncology |
 |
| Hospital Title | Associate in Medicine | |
| Academic Title | Professor of Pediatrics | |
| Phone | 617-714-7050 | |
| Fax | 617-714-8955 | |
| Todd Golub | ||
| Location |
7 Cambridge Center Cambridge MA 02115 |
Research Overview
Todd Golub's laboratory focuses on the genetic basis of cancer, with particular emphasis on the utilization of new genomics and computer science approaches to cancer diagnosis and treatment planning. The laboratory has pioneered the use of DNA microarrays, or 'DNA chips,' for cancer diagnosis and is currently extending these techniques to gain insight into the molecular basis of human cancer. Part of this research effort involves the integration of computer science experts into the research group to extract clinically meaningful patterns from complex genetic information within tumors.
About Todd Golub
Todd Golub received his MD from the University of Chicago Pritzker School of Medicine. He competed an internship, residency, and fellowship at Children's Hospital Boston/Dana-Farber Cancer Institute.
Todd is the recipient of multiple awards, including the 2009 AACR-Richard and Hinda Rosenthal Memorial Award, 2008 E. Mead Johnson Award from the Society for Pediatric Research, the 2007 Oski Prize of the American Society of Pediatric Hematology-Onocology, Discover Magazine’s Inventor of the Year (Health Category), the Daland Prize of the American Philosophical Society, the Outstanding Achievement Award from the American Association for Cancer Research, and the 2007 Paul Marks Prize for Cancer Research. Todd also serves on the Board of Scientific Advisors of the National Cancer Institute.
Key Publications
- Hoshida Y, Villanueva A, Kobayashi M, Peix J, Chiang DY, Camargo A, Gupta S, Moore J, Wrobel MJ, Lerner J, Reich M, Chan JA, Glickman JN, Ikeda K, Hashimoto M, Watanabe G, Daidone MG, Roayaie S, Schwartz M, Thung S, Salvesen HB, Gabriel S, Mazzaferro V, Bruix J, Friedman SL, Kumada H, Llovet JM, Golub TR. Gene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma. N Engl J Med. 2008 Nov 6;359(19):1995-2004. Epub 2008 Oct 15. PubMed PMID: 18923165.
- Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, Lerner J, Brunet JP, Subramanian A, Ross KN, Reich M, Hieronymus H, Wei G, Armstrong SA, Haggarty SJ, Clemons PA, Wei R, Carr SA, Lander ES, Golub TR. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 2006 Sep 29;313(5795):1929-35. PubMed PMID: 17008526.
- Ebert BL, Pretz J, Bosco J, Chang CY, Tamayo P, Galili N, Raza A, Root DE, Attar E, Ellis SR, Golub TR. Identification of RPS14 as a 5q- syndrome gene by RNA interference screen. Nature. 2008 January 17;451(7176):335-339. PubMed PMID:18202658.
