DNA photo
  Children's Hospital Research  Children's Hospital Labs
David G. Nathan, MD  Children's logo  Harvard logo
 David G. Nathan, MD
 X  X
   Department  Hematology/Oncology
   Hospital Title  President Emeritus,
Dana-Farber Cancer Institute
   Academic Title  Robert A. Stranahan
Distinguished Professor of Pediatrics
   Phone  617-632-2155
   Fax  617-632-4367
   Email  David Nathan
   Location  Dana-Farber Cancer Institute
44 Binney Street
Boston MA 02115
Research Overview
Dr. Nathan no longer operates a research laboratory. Most of his academic effort is devoted to teaching students, house staff and fellows, mentoring young faculty members, and writing text book chapters, books and short articles. He and Stuart Orkin write a monthly column for Genome Medicine, an on-line journal. He continues his interest in the congenital and acquired bone marrow failure syndromes and the hemoglobinopathies. He has recently submitted a program project grant of which he is the PI devoted to an entirely new treatment of sickle cell crisis based on interference with iNKT cell function. He remains involved in policies concerning clinical research.
About David Nathan

David Nathan received an MD from Harvard Medical School. He completed an internship and residency at Brigham and Women's Hospital and a fellowship at the National Cancer Institute.

He is the recipient of numerous awards, including the National Medal of Science, 1990; the American Philosophical Society, 1999; the Annual Award for Excellence in Clinical Research, NIH, 1996; the Henry Stratton Medal, American Society of Hematology, 1995; the John Howland Medal of the American Pediatric Society 2003, and the George Kober Medal of the Association of American Physicians 2006.

Key Publications
  • Nathan DG. Search for improved therapy of sickle cell anemia. Journal of Pediatric Hematology and Oncology 2002; 24: 700-703.

  • Shimamura A, Montes de Oca R, Svenson JL, Haining N, Moreau LA, Nathan DG, D'Andrea AD. A novel diagnostic screen for defects in the Fanconi anemia pathway. Blood 2002; 100: 4649-4654.

  • Gazda H, Lipton JM, Willig TN, Ball S, Niemeyer CM, Tchernia G, Mohandas N, Daly MJ, Ploszynska A, Orfali KA, Vlachos A, Glader BE, Rokicka-Milewska R, Ohara A, Baker D, Pospisilova D, Webber A, Viskochil DH, Nathan DG, Beggs AH, Sieff CA. Evidence for linkage of familial Diamond-Blackfan anemia to chromosome 8p23.3-p22 and for non-19q non-8p disease. Blood 2001; 97: 2145-2150.

  • Nathan DG. Acceptance of the 2006 Kober medal. J Clin Invest. 2007 Apr;117(4):1107-13.

  • Nathan DG. The several Cs of translational clinical research. J Clin Invest. 2005 Apr;115(4):795-7.

  • Cunningham MJ, Nathan DG. New developments in iron chelators. Curr Opin Hematol. 2005 Mar;12(2):129-34.
 X  X