Featured Science and Innovations
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Christopher Walsh discusses autism research in Middle Eastern families A recent Children's Hospital Boston study, involving 88 large Middle Eastern families, has implicated a half-dozen new genes in autism. In this interview, Walsh discusses the challenges of autism genetics, what the findings mean, and the concept of multiple "autisms" which may benefit from different treatment approaches. |
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CHIP researchers discuss the power and potential of bioinformatics Using powerful computational tools and a variety of databases -- from insurance claims files to pharmacy records to real-time emergency-room data -- Kenneth Mandl, PhD, MPH and John Brownstein, PhD, have made a variety of discoveries, many of them unexpected, and all of them relevant to public health. |
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A tissue-engineering approach to breast cancer therapy Donald Ingber, MD, PhD, of the Children's Vascular Biology Program, is investigating the use of tissue engineering to treat breast cancer--an approach that could potentially transform the cancer field. His vision is to create materials that could be implanted or injected to "reboot" the cancer, causing it to revert into normal breast tissue. |
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David Williams discusses taking pediatric research from bench to bedside David Williams, MD, discusses the importance of bridging the translational gap, the challenges in doing so, and how Children's plans to accelerate this process in the future. He also speaks to the need for more research funding for pediatrics. |
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Bruce Zetter remembers Dr. Folkman Bruce Zetter, PhD, Children's Hospital Boston's chief scientific officer, joined Judah Folkman's laboratory in 1978. In this interview, Dr. Zetter discusses what it was like to work in the lab, the impact Dr. Folkman had on cancer research, and his thoughts on Dr. Folkman and the Nobel Prize. |
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Controlling cell function with a magnet In this interview, Donald Ingber, MD, PhD, describes the new "nanobiotechnology" that enables magnetic control of events at the cellular level. The technology, says Ingber, could lead to non-invasive ways of controlling drug release or physiologic processes such as heart rhythms and muscle contractions. |
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Christopher Walsh and Bernard Chang on dyslexia Forms of dyslexia that are marked by poor reading fluency may be caused by disorganized, meandering tracts of nerve fibers in the brain, according to Christopher Walsh, MD, PhD, (left) and Bernard Chang, MD. Their study gives researchers a glimpse of what may go wrong in the structure of some dyslexic readers' brains. |
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George Daley on Korean stem cells' true source Research led by George Daley, MD, PhD, and Kitai Kim, PhD, sheds new light on the now-discredited Korean embryonic stem cell lines. In this video interview, Daley discusses the Korean research and how the Korean stem cells were actually created through parthenogenesis, a process that creates an embryo from an unfertilized egg. |
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Judah Folkman on angiogenesis Dr. Judah Folkman, director of Children's Program in Vascular Biology, originated the groundbreaking idea that angiogenesis is also central to the development and growth of tumors. In this interview, Dr. Folkman discusses the history of angiogenesis in cancer research, where the research is headed, and he recounts a couple of personal anecdotes. |
