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Department
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Genetics and Endocrinology
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Hospital Title
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Director of the Phenotype Core of the Program in Genomics
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Academic Title
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Assistant Professor of Pediatrics
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Phone
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617-919-2338
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Fax
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617-730-0245
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Email
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Ingrid Holm
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Location
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300 Longwood Avenue
Enders 5
Boston MA 02115
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Ingrid Holm's research focuses on the genetics of bone disorders. She has performed research in the role of mutations in the PHEX gene in hypophosphatemic rickets. Her studies have sought to elucidate the genetic and environmental components of disorders of bone mineralization. She is particularly interested in the contribution of enviromental factors to the low bone mass seen in indiviuals with neuromuscular diseases, such as muscular dystrophy.
Dr. Holm is interested in the genetics of complex traits. As director of the Phenotype Core of the Program in Genomics, she has worked with researchers to develop clinical genetic research projects in diabetes, autism, congenital heart disease, and atopic dermatitis, and has her own project in the genetic contributions to congenitial hip dysplasia.
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Ingrid Holm received her MD degree from the University of California, Los Angeles. She completed an internship, residency, and post-graduate fellowships in genetics and pediatric endocrinology at Children's Hospital Boston. She received an MPH degree from Harvard School of Public Health.
Dr. Holm is Past President of Advances in Mineral Metabolism, an organization of professionals in the field of mineral metabolism.
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- Holm IA. Challenges in clinical assessment of bone density and quality in children. Current Opinion in Endocrinology and Diabetes. 2006;13:15-20
- Holm IA, Manson, JE, Michels, KB, Alexander EK, Willett, WC, Utiger RD. Smoking and Other Lifestyle Factors and the Risk of Graves Hyperthyroidism. Archives of Internal Medicine, 2005;165:1606-11.
- Holm IA, Nelson AE, Robinson BG, Mason RS, Marsh DJ, Cowell CT, Carpenter TO. Mutational analysis and genotype-phenotype correlation of the PHEX gene in X-linked hypophosphatemic rickets. Journal of Clinical Endocrinology & Metabolism 2001. 86: 3889-3899
- Holm IA, Huang X, Kunkel LM. Mutational analysis of the PHEX gene in patients with X-linked hypophosphatemic rickets. American Journal of Human Genetics 1997; 60: 790-797.
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