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Children's Hospital Research Children's Hospital Labs
Marian Neutra, PhD Children's logo Harvard logo
Marian Neutra, PhD
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   Department  Gastroenterology/Nutrition
   Hospital Title  Director, Gastrointestinal
Cell Biology Research Laboratory
   Academic Title  Ellen and Melvin Gordon
Distinguished Professor of Pediatrics
   Phone  617-355-6229
   Fax  617-730-0498
   Email  Marian Neutra
   Location  300 Longwood Avenue
Enders-12
Boston MA 02115
Research Overview
Marian Neutra's research is directed at defining mucosal immunity in order to better understand and prevent HIV infection. She has explored the specialized systems of immunity that control infections at mucosal surfaces of the body, including the intestines, lungs and genitourinary tract. Dr. Neutra's work provides a basis for understanding how certain pathogens evade the immune system and builds a foundation for developing more effective oral vaccines.
About Marian Neutra

Marian Neutra received her PhD in cell biology and histology from McGill University.

Dr. Neutra is also director of the Harvard Digestive Diseases Center and serves on the AIDS Research Advisory Council of the National Institutes of Health. She was awarded an an honorary Doctor of Sciences degree from Carleton College in 2004.
Key Publications
  • Mantis NJ, Cheung MC, Chintalacharuvu KR, Rey J, Corthesy B, Neutra MR. Selective adherence of IgA to murine Peyer's patch M cells: evidence for a novel IgA receptor. Journal of Immunology 2002. 169: 1844-1851.

  • Hutchings AB, Helander A, Silvey KJ, Chandran K, Lucas WT, Nibert ML, Neutra MR. Secretory immunoglobulin A antibodies against the sigma1 outer capsid protein of reovirus type 1 Lang prevent infection of mouse Peyer's patches. Journal of Virology 2004. 78: 947-957.

  • Helander A, Silvey KJ, Mantis NJ, Hutchings AB, Chandran K, Lucas WT, Nibert ML, Neutra MR. The viral sigma1 protein and glycoconjugates containing alpha2-3-linked sialic acid are involved in type 1 reovirus adherence to M cell apical surfaces. Journal of Virology 2003; 77: 7964-77.
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