Research Faculty

Edward Y. Lee, MD, MPH

Department Radiology
Hospital Title Staff Radiologist
Academic Title Assistant Professor of Radiology
Phone 617-355-6286
Fax 617-730-0573
Email Edward Y. Lee
Location 300 Longwood Avenue
Main 2
Boston, MA 02115

Research Overview

Edward Lee's primary research interest is in developing novel imaging techniques and modalities aimed at improving diagnostic capabilities, therapeutic options, and ultimately, patient outcomes in children with various thoracic diseases.

Dr. Lee's current work is in testing the technical feasibility and clinical applicability of MRI using hyperpolarized gases (e.g., 3He and 129Xe) as an innovative new contrast agent to better visualize airspaces within the lungs. The overall goal of his study is to determine if using hyperpolarized gases for MR imaging facilitates more timely diagnoses and better monitoring of various lung disease processes without associated ionizing radiation, particularly important in children.

In addition to his current research pursuits, Dr. Lee has also worked with Multidetector CT (MDCT) extensively in order to evaluate pediatric patients with mediastinal vascular anomalies and central airway abnormalities such as airway stenosis and tracheobronchomalacia.

About Edward Lee

Edward Lee is an assistant professor of Radiology at Harvard Medical School and Children's Hospital Boston. He received his A.B. and M.D. from the University of Chicago and his M.P.H. from Harvard University, followed by an internship at Harvard Medical Center (BIDMC/BWH/DFCI) and radiology residency at Mallincrodt Institute of Radiology / Washington University Medical Center. Dr. Lee, as a chief fellow, also completed a pediatric radiology fellowship at Children's Hospital Boston.

Dr. Lee was awarded research grants from the Society for Pediatric Radiology (SPR), Association of University Radiologists and GE Health Care (GERRAF), and the Society of Thoracic Radiology (STR).

Key Publications

  • Lee EY, Tracy DA, Mahmood SA, Weldon CB, Zurakowski D, Boiselle PM. Preoperative MDCT evaluation of congenital lung anomalies in children: comparison of axial, multiplanar, and 3D images. AJR Am J Roentgenol. 2011; 196(5): 1040 - 1046.
     
  • Lee EY, Tracy DA, Eisenberg RL, Arellano CM, Mahmood SA, Cleveland RH, Zurakwoski D, Boiselle PM. Screening of asymptomatic children for tuberculosis: is a lateral chest radiograph routinely indicated? Acad Radiol. 2011; 18(2): 184 - 190.
     
  • Lee EY, Khatwa U, McAdam AJ, Bastos M. Mahmood SA, Ervoes JP, Boiselle PM. Streptococcus milleri group pleuropulmonary infection in children: computed tomographic findings and clinical features. J Comput Assist Tomogr. 2010; 34(6): 927 - 932.
  • Lee EY, Zurakowski D, Boiselle PM. Pulmonary embolism in pediatric patients: survey of CT pulmonary angiography practices and policies. Acad Radiol. 2010; 17(12) 1543 - 1549.
  • Lee EY, Kritsaneepaiboon S, Arellano CM, Grace RF, Zurakowski D, Boiselle PM. Unsuspected pulmonary emboli in pediatric oncology patients: detection with MDCT. AJR Am J Roentgenol. 2010; 194(5): 1216 - 1222.
  • Lee EY, Tracy DA, Bastos M, Casey AM, Zurakowski D, Boiselle PM. Expiratory volumetric MDCT evaluation of air trapping in pediatric patients with and without tracheomalacia. AJR Am J Roentgenol. 2010; 194(5): 1210 - 1215.
  • Lee EY, Boiselle PM, Shamberger RC. Multidetector computed tomography and 3-dimensional imaging: preoperative evaluation of thoracic vascular and tracheobronchial anomalies and abnormalities in pediatric patients. J Pediatr Surg. 2010; 45(4): 811 - 821.
  • Lee EY, Strauss KJ, Tracy DA, Bastos M, Zurakowski D, Boiselle PM. Comparison of standard-dose and reduced-dose expiratory MDCT techniques for assessment of tracheomalacia in children. Acad Radiol. 2010; 17(4): 504 - 510.
  • Lee EY, McAdam AJ, Chaudry G, Fishman MP, Zurakowski D, Boiselle PM. Swine-origin influenza A (H1N1) viral infection in children: initial chest radiographic findings. Radiology. 2010; 254(3): 934 - 941.
  • Lee EY, Zurakowski D, Diperna S, d'Almeida Bastos M, Strauss KJ, Boiselle PM. Parenchymal and pleural abnormalities in children with and without pulmonary embolism at MDCT pulmonary angiography. Pediatr Radiol. 2010; 40(2): 173 - 181.
  • Lee EY, Kritsaneepaiboon S, Zurakowski D, Arellano CM, Strauss KJ, Boiselle PM. Beyond the pulmonary arteries: alternative diagnoses in children with MDCT pulmonary angiography negative for pulmonary embolism. AJR Am J Roentgenol. 2009; 193(3): 888 - 894.
  • Lee EY, Boiselle PM. Tracheobronchomalacia in Infants and Children: Multidetector CT Evaluation. Radiology 2009; 252(1): 7 - 22.
  • Lee EY, Sun Y, Zurakowski D, Hatabu H, Khatwa U, Albert MS. Hyperpolarized 3He MR Imaging of the Lung: Normal Range of Ventilation Defects and PFT Correlation in Young Adults. J Thorac Imaging 2009; 24(2): 110 - 114.
  • Lee EY, Litmanovich D, Boiselle PM. Multidetector CT Evaluation of Tracheobronchomalacia. Radiol Clin North Am 2009; 47(2): 261-269.
  • Lee EY, Zurakowski D, Waltz DA, Mason KP, Riaz F, Ralph A, Boiselle PM. MDCT evaluation of the prevalence of tracheomalacia in children with mediastinal aortic vascular anomalies. J Thorac Imaging 2008; 23(4):258-265.
  • Lee EY, Boiselle PM, Cleveland RH. MDCT Evaluation of Congenital Lung Anomalies. Radiology 2008; 247(3): 632-648.
  • Lee EY, Siegel MJ, Hildebolt CF, Gutierrez FR, Fallah JH, Bhalla S. Evaluation of thoracic aortic anomalies in pediatric patients and young adults: Comparison of axial, multiplanar, and 3D images. AJR Am J Roentgenol. 2004; 183: 777-784.
  • Lee EY, Siegel MJ, Chu CM, Gutierrez FR, Kort HW. Amplatzer Atrial Septal Defect Occluder for Pediatric Patients: Radiologic Appearance. Radiology 2004; 233(2): 471 - 476.
  • Lee EY, Siegel MJ, Sierra LM, Foglia RP. Evaluation of Angioarchitecture of Pulmonary Sequestration in Pediatric Patients Using 3D MDCT Angiography. AJR Am J Roentgenol. 2004; 183(1): 183 - 188.