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  Children's Hospital Research  Children's Hospital Labs
Jay Wilson, MD  Children's logo  Harvard logo
 Jay Wilson, MD
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   Department  General Surgery
   Hospital Title  Director, Lung Growth Laboratory
   Academic Title  Associate Professor of Surgery
   Phone  617-355-7800
   Fax  617-730-0477
   Email  Jay Wilson
   Location  300 Longwood Avenue
Fegan-3
Boston MA 02115
Research Overview
The focus of Jay Wilson's research is to increase lung capacity in children who are born with underdeveloped lungs due to conditions such as congenital diaphragmatic hernia. He pioneered the use of perfluorocarbon--an oxygen-dissolving liquid--to stretch the lungs of premature infants who had difficulty being weaned from ECMO.

Recently, his focus has turned to elucidating the molecular process of fetal and newborn lung growth, so that these processes might be harnessed to stimulate lung growth in children with congenital disorders.

About Jay Wilson
Jay Wilson received his MD degree from Albert Einstein College of Medicine. He completed an internship and residency at Brigham and Women's Hospital and a fellowship at Children's Hospital Boston.
Key Publications
  • Fuchs JR, Kaviani A, Oh JT, LaVan D, Udagawa T, Jennings RW, Wilson JM, Fauza DO. Diaphragmatic reconstruction with autologous tendon engineered from mesenchymal amniocytes Journal of Pediatric Surgery 2004;  39: 834-837.

         
  • Muratore CS, Nguyen HT, Ziegler MM, Wilson JM. Stretch-induced upregulation of VEGF gene expression in murine pulmonary culture: a role for angiogenesis in lung development. Journal of Pediatric Surgery 2000; 35: 906-913.

  • Nobuhara KK, Fauza DO, DiFiore JW, Hines MH, Fackler JC, Slavin R, Hirschl R, Wilson JM. Continuous intrapulmonary distension with perfluorocarbon accelerates neonatal (but not adult) lung growth. Journal of Pediatric Surgery 1998; 33: 292-298.
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