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Home
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About the Program
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Investigators & Labs
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Louis M. Kunkel, PhD
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Alan H. Beggs, PhD
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Elizabeth C. Engle, MD
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Chao-Yu Guo, PhD
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Emanuela Gussoni, PhD
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Joel Hirschhorn, MD, PhD
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Ingrid A. Holm, MD, MPH
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Isaac Kohane, MD, PhD
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Kyriacos Markianos, PhD
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Interdisciplinary Projects
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Cores
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Family & Patient Info
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How to Help
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Affiliate Members
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Contact Us
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Elizabeth Engle's research focuses on uncovering the genetic causes of common and complex strabismus. In particular, the lab's primary goal has been to understand the molecular basis of a group of pediatric eye movement disorders referred to as the congenital cranial dysinnervation disorders (CCDDs). To that end, research projects in the Engle laboratory include family studies to locate and identify the genes mutated in the various forms of these disorders. Once a gene is identified, they study its normal and abnormal protein product to determine the role of the gene in health and disease.
