DNA photo
  Children's Hospital Research  Children's Hospital Labs
Silberstein Laboratory  Children's logo  Harvard logo
 Home
 X  X
Yi Le, M.D., Ph.D. - Research Associate
Education
1989 M.D. Nanfang Medical University
1999 Ph.D. National University of Singapore
Publications
  • Le Y, Chen Y, Zhou M. (1994) Protection and immunoregulation of polysaccharide from Coriolus Versicolor on murine peritoneal macrophages attacked by O-LDL. Academic Journal of the First Medical College of PLA. 14(1):12-14.
  • Le Y, Zhou M, Chen Y. (1994) Effects of minimally modified and oxidized low density lipoprotein on lipopolysaccharide-induced tumor necrosis factor and nitric oxide production by peritoneal macrophages of mice. Journal of Arteriosclerosis. 2(2-3):72-76.
  • Yuan C, Mei Z, Lui S, Le Y. (1996) PSK protects macrophages from lipoperoxide accumulation and foam cell formation caused by oxidatively modified low-density lipoprotein. Atherosclerosis. 2;124(2):171-181.
  • Lu J, Le Y, Kon OL, Chan J, Lee SH. (1996) Biosynthesis of human ficolin, an Escherichia coli-binding protein, by monocytes: comparison with the synthesis of two macrophage-specific proteins C1q and the mannose receptor. Immunology. 89(2):289-294.
  • Jin L, Le Y, Zhang W. (1997) Effect of Polydatin on free calcium dynamic changes in lipopolysaccharide-stimulated single macrophages. Academic Journal of the First Medical College of PLA. 17(2):103-105.
  • Le Y, Tan SM, Lee SH, Kon OL, Lu J. (1997) Purification and binding properties of a human ficolin-like protein. Journal of Immunological Methods. 12;204(1):43-49.
  • Lu J and Le Y. (1998) Ficolins and the fibrinogen-like domain. Immunobiology. 199(2):190-199.
  • Le Y, Tan SM, Lee SH, Kon OL, Lu J. (1998) Human L-ficolin: plasma levels; sugar specificity, and assignment of its lectin activitiy of the fibrinogen-like domain (FBG) domain. FEBS Letter. 27;425(2):367-370.
  • Teh C, Le Y, Lee SH, Lu J. (2000) M-ficolin is expressed on monocyte and is a lectin binding to GlcNac and mediates monocyte adhesion and phagocytosis of E. coli. Immunology. 101:225.
  • Honczarenko M, Le Y, Glodek A, Majka M, Campbell JJ, Ratajczak MZ, Silberstein LE. (2002) Macrophage Inflammatory Protein (MIP)-1beta modulate stromal cell-derived factor (SDF)-1 induced responses of progenitor B cells in human bone marrow through heterologous desensitization of CXC chemokine receptor 4 (CXCR4). Blood. 100:2321-2329.
  • Glodek A, Honczarenko M, Le Y, Campbell JJ, Silberstein LE. (2003) Sustained activation of cell adhesion is a dfferentially regulated process in B lymphopoiesis. The Journal of Experimental Medicine. 197(4):461-473.
  • Le Y, Honczarenko M, Glodek A, Ho DK, Silberstein LE. (2005) CXCL12-induced FAK activation and segregation into membrane domains is modulated by RGS1 in REH Pro-B cells. Journal of Immunology. 174(5):2582.
  • Chang HC, Tan K, Ouyang J, Parisini E, Liu JH, Le Y, Wang X, Reinherz EL, Wang HJ. (2005) Structural and mutational analyses of a CD8alphabeta heterodimer and comparison with the CD8alphabeta homodimer. Immunity. 23(6):661-671.
  • Honczarenko M, Le Y, Swierkowski M, Ghiran I, Glodek A, Silberstein LE. (2006) Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors. Stem Cells. 24(4):1030-1041.
  • Zhu D, Hattori H, Jo H, Jia Y, Subramanian KK, You J, Le Y, Honczarenko M, Silberstein LE, Luo HR. (2006) Deactivation of P13K/Akt signaling mediates neutrophil spontaneous death. Proc. Natl. Acad. Sci. USA. 103(40):14836-14841.
 X  X