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Department
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Ophthalmology
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Hospital Title
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Academic Title
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Assistant Professor
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Phone
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617-919-2530
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Fax
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617-730-9117
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Email
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Gabriel Kreiman
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Location
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1 Blackfan Circle
Karp 11217
Boston MA 02115
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The intricacy of the neuronal circuitry makes the brain the most complex system ever studied by Science. Consequently and unfortunately, there has been little progress yet towards advancing treatment of the multiple disorders that affect the nervous system. In contrast to other tissues, in the case of the brain we still do not have a thorough and systematic characterization of the architecture of neuronal circuits, how those circuits are formed and how information is stored in these circuits.
The Kreiman lab is interested in understanding how biological networks encode, process and transmit information. There are two main lines of research in the lab: (i) how circuits of neurons represent visual information and (ii) how gene expression is orchestrated, with a particular emphasis on gene expression in the nervous system. The lab uses a combination of mathematical, computational and experimental tools.
Please visit the Kreiman lab Web site for further information, publications, ongoing projects and job opportunities.
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Gabriel Kreiman received his MSc and PhD degree from the California Institute of Technology (Caltech) and subsequently worked as a research fellow at the Massachusetts Institute of Technology (MIT).
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- Kreiman, G. Single neuron approaches to human vision and memories. Current Opinion in Neurobiology, (2007). 17: 471-475
- Serre T, Kreiman G, Kouh M, Cadieu C, Knoblich U, Poggio T, A quantitative theory of immediate visual recognition. Progress In Brain Research, (2007). 165C: 33-56
- Leamey, C., Glendining, K., Kreiman, G., Kang, N., Kuan, H., Fassler, R., Sawatari, A., Tonegawa, S., and Sur, M. (2008). Differential Gene Expression between Sensory Neocortical Areas: Potential Roles for Ten_m3 and Bcl6 in Patterning Visual and Somatosensory Pathways. Cerebral Cortex, 18: 53-66
- Tropea D, Kreiman G, Lyckman A, Mukherjee S, Yu H, Horng S, Sur M. (2006) Distinct gene systems mediating activity-dependent plasticity in visual cortex. Nature Neuroscience 9:660-668
- Quian Quiroga, R., Reddy, L., Kreiman, G., Koch, C., and Fried, I. (2005). Invariant visual representation by single neurons in the human brain. Nature 435, 1102-1107.
- Hung, C., Kreiman, G., Poggio, T., and DiCarlo, J. (2005). Fast Read-out of Object Identity from Macaque Inferior Temporal Cortex. Science 310, 863-866.
- Kreiman, G. (2004). Identification of sparsely distributed clusters of cis-regulatory elements in sets of co-expressed genes. Nucleic Acids Research 32, 2889-2900.
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