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Under the direction of Susan Connolly, MD and Maria Valenza RT, investigators are actively using MRI to non-invasively monitor the healing of joint tissues, including the ACL, and to develop ways to measure the strength of ACL repairs.
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In an animal study, the MRI appearance of the ligament defects treated with collagen-PRP hydrogel was consistent with scar formation in the defect(1), and on the T2 images was different from that seen in the empty defect (scar had medium signal while the fluid was white on T2; Fig 7).
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| click for larger view |
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click for larger view Images courtesy of M. Murray |
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Reference
1. Murray MM, Spindler KP, Devin C, Snyder RB, Muller J, Ballard P, Nanney LB, Zurakowski D: Healing of an intra-articular tissue defect using a stabilized provisional scaffold. J Orthop Res in press, 2006
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