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Children's Hospital Research Children's Hospital Labs
Rana Sharara-Chami Children's logo Harvard logo
Rana Sharara-Chami
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   Department  Anaesthesia
   Hospital Title  Assistant in Critical Care Medicine
   Academic Title  Instructor in Anaesthesia
   Phone  617-355-7327
   Fax  617-730-0453
   Email  Rana Sharara-Chami
   Location  300 Longwood Avenue
Bader 634
Boston MA 02115
Research Overview

Dr. Sharara-Chami research focuses on elucidating the effects of the stress hormone epinephrine by studying a mouse model that was made epinephrine- deficient by disrupting the enzyme that catalyzes epinephrine synthesis.

She works in the lab of Dr. Joseph Majzoub, Chief of the Endocrinology Division at Children's Hospital Boston.

Research Goals
Study the pathophysiology of epinephrine deficiency in the basal state, during metabolic stress and during cardiovascular stress.
Translational Impact
Research will help to better understand the role that epinephrine plays in critically ill patients and to address the requirements for epinephrine infusion during shock.
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