Janet Soul's research is focused on early acquired brain injury in premature and term-born infants, specifically periventricular leukomalacia, intraventricular hemorrhage with posthemorrhagic hydrocephalus, and hypoxic-ischemic brain injury. Her research aims to understand the pathophysiology of such brain injury and detect its earliest onset so that future potential neuroprotective therapies may be administered promptly to the infants at risk for maximal efficacy. Dr Soul is using advanced three-dimensional MRI techniques to determine the structural changes in brain structure related to normal brain development, early acquired brain injury, and the developmental response to such injury (i.e., plasticity in the developing brain).
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About Janet Soul
Janet Soul received her MD from McGill University Faculty of Medicine. She completed an internship and residency at Boston City Hospital and fellowships in neurology and neonatal neurology at Children's Hospital Boston.
Key Publications
Soul JS, Eichenwald E, Walter G, Volpe JJ, Du Plessis AJ. CSF removal in infantile posthemorrhagic hydrocephalus results in significant improvement in cerebral hemodynamics. Pediatric Research 2004; 55: 872-876.
Soul JS, Robertson RL, Tzika AA, du Plessis AJ, Volpe JJ. Time course of changes in diffusion-weighted magnetic resonance imaging in a case of neonatal encephalopathy with defined onset and duration of hypoxic-ischemic insult. Pediatrics 2001; 108: 1211-1214.
Soul JS, Taylor GA, Wypij D., Duplessis AJ, Volpe JJ. Noninvasive detection of changes in cerebral blood flow by near-infrared spectroscopy in a piglet model of hydrocephalus. Pediatric Research 2000; 48: 445-449.
