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  Children's Hospital Research  Children's Hospital Labs
Leonard Rappaport, MD  Children's logo  Harvard logo
 Leonard Rappaport, MD
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   Department  Division of Developmental Medicine
   Hospital Title  Chief,
Division of Developmental Medicine
Director,
Developmental Medicine Center
   Academic Title  Professor
   Phone  617-355-7030
   Fax  617-730-0252
   Email  Leonard Rappaport
   Location  300 Longwood Avenue
Fegan-10
Boston MA 02115
Research Overview

One goal of Leonard Rappaport's work is to gain a better understanding of the effects of medical and surgical interventions on development and neurological status later in childhood. He seeks to use that information to improve developmental and behavioral outcome after infant cardiac surgery.

His lab is also collaborating with Children's Genomics Center and MIT's Department of Brain and Cognitive Sciences to better understand the etiology of developmental disorders. One of the goals of this work is to improve the methods of diagnosing and treating autism spectrum disorders.

Rappaport and colleagues are also investigating the etiology and treatment of elimination disorders such as encopresis and enuresis.

About Leonard Rappaport

Leonard Rappaport received his MD from Yale University School of Medicine. He completed an internship, residency, and fellowship at Childrens Hospital Boston.

Dr. Rappaport serves on the Executive Board for NIH-NHLBI trials in infant heart surgery.

Key Publications
  • Bellinger D, Jonas R, Rappaport L, Wypij D, Wernovsky G, Kuban K, Barnes P, Holmes G, Hickey P, Strand R, Walsh A, Helmers S, Constantinou J, Carrazana E, Mayer J, Hanley F, Casteneda A, Ware J, Newburger JA. Comparison of the developmental and neurologic status at one year of children who underwent heart surgery using hypothermic circulatory arrest or low-flow cardiopulmonary bypass. New England Journal of Medicine 1995; 332: 549-555.

  • Rappaport LD, Wypij D, Jonas R, Bellinger DB, Helmers P, Newburger J. Relation of seizures following cardiac surgery in early infancy to neurodevelopmental outcome. Circulation 1998; 97: 773-779.

  • Landgraf J, Rich M, Rappaport LA. Measuring quality of life in children with ADHD and their families. Archives of Child and Adolescent Pediatrics 2001; 156: 384-391.
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