Tethered Spinal Cord Program Research and Innovation

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In our Tethered Spinal Cord Syndrome Program and throughout our Department of Neurosurgery, our treatment is informed by our scientific research. In fact, Boston Children’s is home to the world’s most extensive research enterprise at a pediatric hospital.

Our neurosurgeons—who are also members of the Harvard Medical School faculty—conduct ongoing research into the causes of, and treatments for, tethered spinal cord syndrome and many other disorders relating to the brain, spine and nervous system. We also collaborate with visionary scientists at Boston’s universities and throughout the surrounding biomedical community. While our individual researchers’ projects cover a broad spectrum of topics, all of our researchers share one goal: to find the best ways to treat children of all ages who are fighting these diseases, while never losing sight of the individual needs of each patient and family.

Here are just a few of current Boston Children's neurosurgery research projects underway with potential implications for children with tethered cord:

  • improving long-term outcomes for children who have suffered neurological trauma
  • examining the role of certain growth factors in spinal cord injuries
  • tracing the activities of cell-signaling pathways in the central nervous system
     

Clinical trials at Boston Children’s

Boston Children’s is known for pioneering some of the most effective techniques in the field of neurosurgery. A significant part of our success comes from our commitment to research—and to advancing the frontiers of what’s possible in neurosurgery by conducting clinical trials.

Boston Children’s conducts hundreds of clinical trials at any given time. Clinical trials are studies that may involve:

  • evaluating the effectiveness of a new drug therapy
  • testing a new diagnostic procedure or device
  • examining a new treatment method for a particular disease
  • taking a closer look at the causes and progression of specific conditions

While children must meet strict criteria in order to be eligible for a clinical trial, your child may be eligible to take part in a study. Before considering this option, you should be sure to:

  • consult with your child’s treating physician and treatment team
  • gather as much information as possible about the specific course of action outlined in the trial
  • do your own research about the latest breakthroughs relating to your child’s condition

If your physician recommends that your child participate in a clinical trial, you can feel confident that the plan detailed for that study represents the best and most innovative care. Taking part in a clinical trial at Children’s is entirely voluntary. Our team will be sure to fully address any questions you may have, and you may remove your child from the medical study at any time.


Find a clinical trial

Search current and upcoming clinical trials at Boston Children’s

Search National Institutes of Health’s clinical trials taking place around the world

Did you know? Boston Children's program helps kids with incontinence issues tied to tethered cord, other disorders

Boston Children's is home to a multidisciplinary program devoted entirely to helping children with urine and bowel incontinence problems as a result of congenital disorders like spina bifida, tethered cord and urological malformations. The Center for Continence of Urine and Bowel (CUB) is staffed by experts from several relevant Children's specialties—such as urology, neurosurgery, gastroenterology and general surgery—and provides comprehensive evaluations, treatments and monitoring for each patient. Learn more about CUB.


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The future of pediatrics will be forged by thinking differently, breaking paradigms and joining together in a shared vision of tackling the toughest challenges before us.”
- Sandra L. Fenwick, President and CEO
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