Neuromuscular Program QED Study

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Boston Children's Hospital Neuromuscular ProgramBoston Children's Hospital is now enrolling school-age healthy boys and boys with DMD to participate in a promising new research study: the Quantitative Ultrasound and Electrical Impedance Myography (QED) Study

This study is aimed at determining whether two pain-free machines are effective in studying nerve and muscle function. We hope to enroll a total of 70 children, 35 of whom have a condition known as Duchenne Muscular Dystrophy and 35 of whom do not.

This study is currently enrolling. 

Read more about the study.

Why is this so important?

Duchenne Muscular Dystrophy (DMD) is a genetic condition that affects a structural component of skeletal muscle cells, causing the muscles to waste away. The loss of muscle causes weakness and can lead to limitations in gross motor abilities, like walking, as well as breathing problems. Children with DMD show signs of muscle weakness as toddlers, and many require wheelchairs by the time they are adolescents. Survival is rare beyond the early 30s.

Researchers have worked hard over the last 15 years to understand the genetics of DMD and to identify possible mechanisms for treatments. Currently, research is happening all over the country to try to find medications that will lessen the symptoms of DMD. 

While these trials are promising, we don’t yet have perfect tools to measure if these medications are effective.  As such, we are hoping two tools, Electrical Impedance Myography (EIM) and Quantitative Ultrasound (QU), will help to change that and be instrumental in future DMD trials.  However, we can’t get there without your help!

What is EIM?

Neuromuscular Program at Boston Children's HospitalElectrical Impedance Myography is a technology used to measure how well a tiny electrical current travels through muscle.  The machine we use is called the SFB7, shown at right. Learn more.


What is QU?

Neuromuscular Program of Boston Children's HospitalQuantitative Ultrasound is a non-invasive imaging technique that captures pictures of bones and muscles, then studies the images mathematically. Learn more.

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