Female Athlete Program | Research Publications

Experts in Boston Children’s Female Athlete Program and the Sports Medicine Division are dedicated to conducting research and developing innovations for athletes of all ages. Primary areas of focus include the ACL/knee, bone health, and concussion and sports injuries. The team has participated in the following research:


Validation of Porcine Knee as a Sex-specific Model to Study Human Anterior Cruciate Ligament Disorders. http://www.ncbi.nlm.nih.gov/pubmed/25269532. Kiapour AM, Shalvoy MR, Murray MM, Fleming BC. Clin Orthop Relat Res. 2014 Oct 1. [Epub ahead of print].

Can Platelet-Rich Plasma Enhance Anterior Cruciate Ligament and Meniscal Repair? http://www.ncbi.nlm.nih.gov/pubmed/25101873. Hutchinson ID, Rodeo SA, Perrone GS, Murray MM. J Knee Surg. 2014 Aug 7. [Epub ahead of print].

Knee Injury Patterns in Young Irish Dancers. http://www.ncbi.nlm.nih.gov/pubmed/24925173. Beasley MA, Stracciolini A, Tyson KD, Stein CJ. Med Probl Perform Art. 2014 Jun; 29(2): 70-3.

Biology of Anterior Cruciate Ligament Injury and Repair. http://www.ncbi.nlm.nih.gov/pubmed/23818453. Murray MM, Fleming BC. J Orthop Res. 2014 Oct; 31(10): 1501-6.

The use of magnetic resonance imaging to predict ACL graft structural properties. Fleming BC, Vajapeyam S, Connolly SA, Magarian EM, Murray MM. J Biomech. 2011 Nov 10;44(16):2843-6.

Effect of anterior cruciate healing on the uninjured ligament insertion site. Haus BM, Mastrangelo AN, Murray MM. J Orthop Res. 2012 Jan;30(1):86-94.

A comparative anatomical study of the human knee and six animal species. Proffen BL, McElfresh M, Fleming BC, Murray MM. Knee. 2011 Aug 16.

Biomechanical outcomes after bioenhanced anterior cruciate ligament repair and anterior cruciate ligament reconstruction are equal in a porcine model. Vavken P, Fleming BC, Mastrangelo AN, Machan JT, Murray MM. Arthroscopy. 2012 Jan 19.

The effect of platelet concentrates on graft maturation and graft-bone interface healing in anterior cruciate ligament reconstruction in human patients: a systematic review of controlled trials. Vavken P, Sadoghi P, Murray MM. Arthroscopy. 2011 Nov;27(11):1573-83.

Treating anterior cruciate ligament tears in skeletally immature patients. Vavken P, Murray MM. Arthroscopy. 2011 May;27(5):704-16.

Bone density

Fractures in Relation to Menstrual Status and Bone Parameters in Young Athletes. http://www.ncbi.nlm.nih.gov/pubmed/25397605. Ackerman KE, Sokoloff NC, De Nardo Maffazioli G, Clarke H, Lee H, Misra M. Med Sci Sports Exerc. 2015 Aug;47(8):1577-86. doi: 10.1249/MSS.0000000000000574.

Hip Structural Analysis in Adolescent and Young Adult Oligoamenorrheic and Eumenorrheic Athletes and Nonathletes. http://www.ncbi.nlm.nih.gov/pubmed/23476076. Ackerman KE, Pierce L, Guereca G, Slattery M, Lee H, Goldstein M, Misra M. J Clin Endocrinol Metab. 2013 Apr; 98(4): 1742-9.

Estradiol level predict bone mineral density in male collegiate athletes: a pilot study. https://www.ncbi.nlm.nih.gov/pubmed/21942923. Ackerman KE, Skrinar GS, Medvedova E, Misra M, Miller KK. Clin Endocrinol (Oxf). 2012 Mar;76(3):339-45.

Higher ghrelin and lower leptin secretion is associated with lower LH secretion in young amenorrheic athletes compared with eumenorrheic athletes and controls. https://www.ncbi.nlm.nih.gov/pubmed/22252944. Ackerman KE, Slusarz K, Guereca G, Pierce L, Slattery M, Mendes Estalla N, Herzog DB, Misra M. Am J Physiol Endocrinol Metab. 2012 Apr 1;302(7):E800-6. doi: 10.1152/ajpendo.00598.2011.

DXA surrogates for visceral fat are inversely associated with bone density measures in adolescent athletes with menstrual dysfunction. https://www.ncbi.nlm.nih.gov/pubmed/21932588. Ackerman KE, Davis B, Jacoby L, Misra M. J Pediatr Endocrinol Metab. 2011;24(7-8):497-504.

Bone microarchitecture is impaired in adolescent amenorrheic athletes compared with eumenorrheic athletes and nonathletic controls. https://www.ncbi.nlm.nih.gov/pubmed/21816790. Ackerman KE, Nazem T, Chapko D, Russell M, Mendes N, Taylor AP, Bouxsein ML, Misra M. J Clin Endocrinol Metab. 2011 Oct;96(10):3123-33.

Bone health and the female athlete triad in adolescent athletes. https://www.ncbi.nlm.nih.gov/pubmed/21378496. Ackerman KE, Misra M. Phys Sportsmed. 2011 Feb;39(1):131-41.

Concussion and sports injuries

Early Symptom Burden Predicts Recovery After Sport-Related Concussion. http://www.ncbi.nlm.nih.gov/pubmed/25381296. Meehan WP 3rd, Mannix R, Monuteaux MC, Stein CJ, Bachur RG. Neurology. 2014 Dec 9; 83(24); 2204-10.

Pediatric Sports Injuries: A Comparison of Males versus Females. http://www.ncbi.nlm.nih.gov/pubmed/24567251. Stracciolini A, Casciano R, Levey Friedman, H, Stein CJ, Meehan WP 3rd, Micheli LJ. Am J Sports Med. 2014 Apr; 42(4): 956-72.


IOC consensus statement on relative energy deficiency in sport (RED-S): 2018 update. https://www.ncbi.nlm.nih.gov/pubmed/29773536. Mountjoy M, Sundgot-Borgen JK, Burke LM, Ackerman KE, Blauwet C, Constantini N, Lebrun C, Lundy B, Melin AK, Meyer NL, Sherman RT, Tenforde AS, Klungland Torstveit M, Budgett R. Br J Sports Med. 2018 Jun;52(11):687-697. doi: 10.1136/bjsports-2018-099193. 

2014 Female Athlete Triad Coalition Consensus Statement on Treatment and Return to Play of the Female Athlete Triad: 1st International Conference held in San Francisco, California, May 2012 and 2nd International Conference held in Indianapolis, Indiana, May 2013. https://www.ncbi.nlm.nih.gov/pubmed/24463911. De Souza MJ, Nattiv A, Joy E, Misra M, Williams NI, Mallinson RJ, Gibbs JC, Olmsted M, Goolsby M, Matheson G. Br J Sports Med. 2014 Feb;48(4):289. doi: 10.1136/bjsports-2013-093218. 

Exercise, sports participation and musculoskeletal disorders of pregnancy and postpartum. https://www.ncbi.nlm.nih.gov/pubmed/22113514. Borg-Stein JP, Fogelman DJ, Ackerman KE. Semin Neurol. 2011 Sep;31(4):413-22.