Celiac Disease Program Research and Innovation

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Contact the Celiac Disease Program

Here at the Celiac Disease Program and Support Group at Children’s Hospital Boston, our care is informed by our research. Children’s is home to the world’s most extensive research enterprise at a pediatric hospital. But as specialists in innovative, family-centered care, our physicians never forget that your child is precious, and not just a patient.

Researchers in the Celiac Disease Program are studying:

  • serologic markers, the identification of which could reduce the need for endoscopies in the diagnosis of celiac disease
  • procedures for taking more reliable biopsies
  • the correlation between people who have had Marsh 1 lesions (sometimes thought of as pre-celiac disease findings) and people who develop celiac disease

Other researchers are examining:

  • how to genetically engineer wheat so that it doesn’t have the proteins that are toxic to people with CD
  • developing a medicine to take with food that may help break down the gluten. This probably won’t work to the point where it can substitute for following a gluten-free diet, but it could offer protection in situations in which you can’t be sure the food is gluten-free.  
  • the possibility of a celiac disease vaccine that could be used as prevention and treatment

Celiac Disease Clinical Trials

We are currently closed for recruitment. Click the links below to learn more about each study:

  • Clinical Outcomes of Children with Marsh 1 Histopathology
  • Prospective Study of Serologic Markers in the Diagnosis of Childhood Celiac Disease

You can also conduct your own search for a clinical trial based on keywords and/or departments.

Read more about clinical research at Boston Children's Hospital.

The future of pediatrics will be forged by thinking differently, breaking paradigms and joining together in a shared vision of tackling the toughest challenges before us.”
- Sandra L. Fenwick, President and CEO

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