The Bone Health Program has been actively involved in exploring the causes and symptoms of pediatric low bone density and researching new and improved treatments. Recent research interests have included:
- Effect of Biomechanical Stimulation on Skeletal Health in Adolescent and Young Women with Anorexia Nervosa:
A randomized, double-blind placebo-controlled trial to measure the healthy adolescents with anorexia nervosa.
- Effect of Hormonal Add-Back Therapy in Adolescents Treated with (GnRH) Agonist Therapy for Endometriosis:
A randomized, double-blinded trial to measure the bones of healthy adolescents with patients with diseases, like anorexia nervosa and endometriosis can be compared.
A Novel Diet-Phenotype Interaction Affecting Body Weight:
How people with different blood insulin levels after consuming carbohydrate respond to different diets for weight loss is compared.
Use of Farnesyltransferase inhibitor (FTI) Lonafarnib for Hutchinson-Gilford Progeria Syndrome (HGPS) and progeroid laminopathies:
This protocol measures an experimental drug's effect using many tests in hopes that this drug will have therapeutic effect on progeria.
Effect of Adrenal and Gonadal Hormones on Bone Marrow and Appendicular BMD:
A randomized, double-blinded trial to find a way to prevent bone loss in patients with the eating disorder, anorexia nervosa.
The Bone Health Program at Boston Children's Hospital has recently acquired a research PQCT (Peripheral Quantitative Computed Tomography) scanner, an innovative machine that measures bone strength and quality, including bone mineral density. The procedure is painless and usually takes 3 - 5 minutes to complete.
We would like to thank The Children's Hospital League for their continued support and partnership with the Bone Health Program and for generously providing us with the funds to purchase the PQCT scanner. The scanner will allow us to conduct important research studies on bone health.