Neonatal And Congenital Anomaly Neurosurgery Program | Research and Innovation

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Contact the Neonatal and Congenital Anomaly Neurosurgery Program

  • 1-617-355-6008
  • International: +1-617-355-5209

Our pioneering research

Dr. Warf and his Boston Children's Hospital colleagues have identified that Endoscopic Third Ventriculostomy/Choroid Plexus Cauterization (ETV/CPC) prevents shunt dependence in many children, including those with no urgent access to subspecialty care for shunt malfunction - particularly in resource-limited environments.

Our research is now translating to optimal treatment selection and outcomes for children with hydrocephalus worldwide.

Dr. Warf is currently involved in the following clinical trials:

  • Prospective Trial of Combined Endoscopic Third Ventriculostomy and Choroid Plexus Cauterization (ETV/CPC) for Treatment of Post-hemorrhagic Hydrocephalus of Prematurity (PHHP) [Protocol #: X10-09-0449]
  • Outcomes in Patients Undergoing Surgical Intervention for Chiari Type I Malformation with Syringomyelia [Protocol #: X09-12-0639]

Innovative treatment for infants with hydrocephalus: ETV/CPC

Boston Children's Neonatal and Congenital Anomaly Neurosurgery Program Director Benjamin Warf, MD, developed a novel surgical technique for treating hydrocephalus in infants, combining endoscopic third ventriculostomy with bilateral choroid plexus cauterization (ETV/CPC).

ETV/CPC involves the use of an endoscope to create an opening in the floor of the third ventricle and combined with endoscopic cauterization of the choroid plexus (CP) at the time of the ETV.

Cauterization of the CP tissue in the lateral ventricles of the brain has been demonstrated to decrease cerebrospinal fluid (CSF) production. This combined procedure addresses both production and absorption issues to return the flow of CSF in the brain to a normal state. The combined procedure is shown to be a more effective treatment in infants then ETV alone.

Learn more about ETV/CPC.

We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”
- Sandra L. Fenwick, President and CEO

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