Division of Gastroenterology, Hepatology and Nutrition A Prospective Case-controlled Study To Identify Novel Biologic Markers Associated With Eosinophilic Esophagitis

LIke ThisLIke ThisLIke ThisLIke ThisLIke This

Contact the Division of Gastroenterology, Hepatology and Nutrition

  • 1-617-355-6058
  • Schedule an Appointment:
    Monday-Friday 7:00am-8:00pm
  • Saturday 9:30am-6:00pm
  • Visit all of our locations

Principal Investigator: Samuel Nurko, MD, MPH

Department: Gastroenterology

Protocol Status: Open for recruitment

Trial Description: Eosinophilic esophagitis (EE) is an inflammatory disease of the esophagus, leading to swallowing problems, pain, food intolerance, and poor weight gain or weight loss in otherwise healthy infants and children. Currently, the only way doctors have to detect and monitor disease activity in patients with EE is by doing an upper endoscopy. This means that patients with EE will typically undergo three to four endoscopies per year. The objective of this study is to develop a laboratory test for EE, so that patients with EE will not need to undergo repeated procedures to monitor the course of their disease.

Recruitment Info: Children between the ages of 1 and 18 years who receive an esophagogastroduodenoscopy (EGD) to evaluate symptoms of esophagitis may be eligible for this study. The study involves the collection of blood, urine, and saliva samples, as well as gastric juice and two esophageal biopsies. The collection of these samples occurs while the patient is under sedation or general anesthesia. Compensation includes a $25 gift card and a parking voucher.

Recruitment Contact: Katharine Rooney

Recruitment Contact Phone: (617) 355-5998

Recruitment Contact Email: Katharine.Rooney@childrens.harvard.edu

We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”
- Sandra L. Fenwick, President and CEO

Boston Children's Hospital
300 Longwood Avenue, Boston, MA 02115
For Patients: 617-355-6000
For Referring Providers: 844-BCH-PEDS | 844-224-7337