Division of Gastroenterology, Hepatology and Nutrition Comparison Of Fibroscan And Serum Fibrosis Markers With Histological Evaluation Of Liver Fibrosis In Pediatric Patients Presenting For Liver Biopsy

LIke ThisLIke ThisLIke ThisLIke ThisLIke This

Contact the Division of Gastroenterology, Hepatology and Nutrition

  • 1-617-355-6058
  • Schedule an Appointment:
    Monday-Friday 7:00am-8:00pm
  • Visit all of our locations

Principal Investigator: Maureen Jonas, MD

Department: Gastroenterology, Center for Childhood Liver Disease

Protocol Status: Open for Recruitment

Trial Description: This is research into other ways to detect cirrhosis, or the degree of liver fibrosis. The study uses a combination of special research blood tests and a technology called “transient elastography” to assess the severity of liver scarring.  The elastography is done with a machine called a “FibroScan” (Echosens, Paris, France), that uses ultrasound technology to measure the stiffness of the liver.

The objective of this study is to determine if liver stiffness as measured by elastography correlates to the amount of scarring (fibrosis) seen on the liver biopsy.  If it does, in the future some liver biopsies may be avoided.

Protocol Status:  Open for recruitment

Recruitment Info: The patient must have had a liver biopsy within 1 year of the study.  In addition, subjects may not be pregnant, have ascites (fluid in the abdomen) or a BMI greater than 35.

PI contact: Maureen Jonas, MD, Center for Childhood Liver Disease

PI Phone: 617-355-5837 

We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”
- Sandra L. Fenwick, President and CEO

Boston Children's Hospital 300 Longwood Avenue, Boston, MA 02115 617-355-6000 | 800-355-7944