Dana-Farber/Boston Children's Cancer and Blood Disorders Center is a partnership between two organizations with a rich and storied history of innovation. Some innovations have come from clinical trials that have led to more effective drugs and therapies. Others from moments spent at the bedside, when doctors and nurses see opportunities to improve current treatment methods. Some of our discoveries and achievements:
Discovering a drug that may enhance the recovery of a child’s blood and immune system, an important advance in stem cell transplantation
Improving leukemia cure rates and reducing chemotherapy-related side effects
Identifying and applying antiangiogenic treatments (drugs that prevent the formation of new blood vessels, which feed tumors) for pediatric brain tumors
The first use of adjuvant chemotherapy (chemotherapy used after surgery to destroy any remaining cancer cells) and limb-salvage surgery for patients with osteosarcoma
Identifying two white blood cell disorders – Shwachman-Diamond syndrome and Diamond-Blackfan syndrome
Discovering a gene for a rare inherited iron deficiency
Together, we carry on this tradition of innovation today through an active clinical trial program and ongoing Care Quality and Patient Safety initiatives.
Visit the Dana-Farber/Boston Children’s website to learn more about our current clinical trials and our proud tradition of research and innovation.
Innovations - The cell from hell: Can we outsmart cancer stem cells?
Some scientists still debate the existence of cancer stem cells – rare cells that can singlehandedly perpetuate a tumor, and possibly make it more aggressive. But others have moved on, isolating candidate cancer stem cells and documenting their distinctive characteristics and markers. Read more.
Quality & Safety
In an effort to make her patients' hospital stay as easy as possible , Dr. Leslie Lehmann and her team have enacted an innovative solution. Each week, she and the unit’s head nurse, conduct Patient Satisfaction Rounds, visiting with each family, and asking directly: What can we be doing better? In the three years they’ve been doing these rounds, significant changes have occurred. Read more