Center for Childhood Liver Disease | Conditions and Treatments

Alagille Syndrome

Alagille syndrome is a genetic disorder of your child’s liver and other organs that causes reduced bile flow because of too few bile ducts inside the liver. The syndrome is usually diagnosed during...

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Alpha-1 Antitrypsin Deficiency (AATD)

Alpha-1 antitrypsin deficiency (AATD) is the lack of a protein made by the liver that’s released into the bloodstream. AATD is a genetic disease that can affect the liver or lung. The alpha-1 protein...

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Biliary atresia

What is biliary atresia? Bile is an important fluid produced by your child’s liver and stored in the gallbladder. In a healthy system, it flows through a tube called the common bile duct to the small...

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Choledochal Cysts

A choledochal cyst is a rare congenital swelling of the hepatic or bile duct of your child’s liver. This is the tract that transports bile produced by the cells to the gallbladder and duodenum (the...

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Cirrhosis of the liver

No parent expects a doctor to say that his or her child has cirrhosis. However, hundreds of children in the United States are diagnosed with cirrhosis – scarring of the liver caused by underlying...

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Cystic Fibrosis

What is cystic fibrosis? Cystic fibrosis (CF) is a common hereditary (inherited) chronic disease that can affect multiple parts of a child’s body — most commonly the lungs and digestive system. ...

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Fatty liver

Your child’s doctor may suspect NAFLD if your child is overweight or obese and routine blood tests suggest that the levels of certain liver enzymes are higher than normal. The diagnosis can sometimes...

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Hepatitis B Virus (HBV)

Thanks to widespread (and now universal) childhood vaccination, the number of new cases of hepatitis B in the United States has dropped dramatically in the last two decades. However, there are still...

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Hepatitis C

For decades, children and adults who appeared at a doctor’s office with a swollen liver or abnormal liver tests and who tested negative for the two major hepatitis viruses – hepatitis A and hepatitis...

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Hepatoblastoma is a rare type of childhood cancer that occurs in the liver. The primary functions of the liver include filtering and storing blood, processing the food we eat and making vital proteins...

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Hepatocellular Carcinoma

Hepatocellular carcinoma is a rare disease in which cancerous cells are found in the tissues of your child’s liver. Although rare, it is the most common primary cancer of the liver. This type of...

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Jaundice is a condition that makes a baby’s skin and the white part of his eyes look yellow. Jaundice occurs when there is a buildup of a brownish yellow substance called bilirubin in a baby’s blood....

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Acute Liver Failure

What is liver failure? Liver failure is severe deterioration of liver function. Liver failure occurs when a large portion of the liver is damaged due to any type of liver disorder. What causes liver...

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Liver tumors

What are liver tumors? Liver tumors are masses occurring in the liver that can be either benign or malignant (cancerous). Tumors that are found at birth or early after delivery are often benign in...

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Portal Hypertension Liver Disease

While liver disease is rare in children, portal hypertension is even less common. For this reason, few centers are able to adequately manage the care of children with this serious condition. Over the...

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Wilson's Disease

Wilson's disease is a rare inherited disorder that can cause liver damage and other life-threatening conditions. In Wilson's disease, your child’s body is unable to excrete excess copper (found in...

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