ACL Program | BEAR (TM) Trial Eligibility Criteria

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Contact the ACL Program

  • 617-355-3501
  • International: +1-617-355-5209
  • Locations

The BEAR (TM) II study is now fully enrolled.

To learn more about the BEAR (TM) II trial or to schedule an appointment with a BEAR(TM) trial physician, please call 617-355-3501 or email

Patients eligible for the study:

  • will be ages 14 to 35, but need to have closed growth plates
  • will have a complete ACL tear which occurred in the past 30 days
  • cannot have a history of prior surgery on the affected knee
  • must not use tobacco, corticosteroids or have a history of diabetes or inflammatory arthritis
  • must not have an allergy to bovine collagen (cow protein)

Patients will be randomly assigned to have the BEAR (TM) procedure (two-thirds of patients) or a standard ACL reconstruction (one-third of patients) and will not be told which group they are in until two years after their surgery.

Boston Children’s is so much more than a hospital—it’s a community of researchers, clinicians, administrators, support staff, innovators, teachers, patients and families, all working together to make the impossible possible. ”
- Sandra L. Fenwick, President and CEO

Boston Children's Hospital
300 Longwood Avenue, Boston, MA 02115
For Patients: 617-355-6000
For Referring Providers: 844-BCH-PEDS | 844-224-7337